Infective endocarditis.


n engl j med 369;8 august 22, 2013 784 shown that antimotility agents can worsen the neurologic outcome in patients in whom the hemolytic–uremic syndrome develops.2 Antimotility agents should not be used in critically ill patients or in those with Clostridium difficile infection. It should also be noted that loperamide is the preferred antimotility agent, since diphenoxylate commonly causes cholinergic side effects without additional antidiarrheal effects.


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